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Epigenetic Inactivation of Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 2 in Lung Cancer and Its Role in Tumorigenesis

BACKGROUND: This study was aimed at investigating the functional significance of heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (HS3ST2) hypermethylation in non-small cell lung cancer (NSCLC). METHODOLOGY/ PRINCIPAL FINDINGS: HS3ST2 hypermethylation was characterized in six lung cancer cell li...

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Detalles Bibliográficos
Autores principales: Hwang, Jung-Ah, Kim, Yujin, Hong, Seung-Hyun, Lee, Jieun, Cho, Yong Gu, Han, Ji-Youn, Kim, Young-Ho, Han, Joungho, Shim, Young Mog, Lee, Yeon-Su, Kim, Duk-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827134/
https://www.ncbi.nlm.nih.gov/pubmed/24265783
http://dx.doi.org/10.1371/journal.pone.0079634