Structural Variation-Associated Expression Changes Are Paralleled by Chromatin Architecture Modifications

Copy number variants (CNVs) influence the expression of genes that map not only within the rearrangement, but also to its flanks. To assess the possible mechanism(s) underlying this “neighboring effect”, we compared intrachromosomal interactions and histone modifications in cell lines of patients af...

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Detalles Bibliográficos
Autores principales: Gheldof, Nele, Witwicki, Robert M., Migliavacca, Eugenia, Leleu, Marion, Didelot, Gérard, Harewood, Louise, Rougemont, Jacques, Reymond, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827143/
https://www.ncbi.nlm.nih.gov/pubmed/24265791
http://dx.doi.org/10.1371/journal.pone.0079973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827143/
https://www.ncbi.nlm.nih.gov/pubmed/24265791
http://dx.doi.org/10.1371/journal.pone.0079973

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