Cargando…
Structural Variation-Associated Expression Changes Are Paralleled by Chromatin Architecture Modifications
Copy number variants (CNVs) influence the expression of genes that map not only within the rearrangement, but also to its flanks. To assess the possible mechanism(s) underlying this “neighboring effect”, we compared intrachromosomal interactions and histone modifications in cell lines of patients af...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827143/ https://www.ncbi.nlm.nih.gov/pubmed/24265791 http://dx.doi.org/10.1371/journal.pone.0079973 |