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Toward Patient-Specific, Biologically Optimized Radiation Therapy Plans for the Treatment of Glioblastoma

PURPOSE: To demonstrate a method of generating patient-specific, biologically-guided radiotherapy dose plans and compare them to the standard-of-care protocol. METHODS AND MATERIALS: We integrated a patient-specific biomathematical model of glioma proliferation, invasion and radiotherapy with a mult...

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Detalles Bibliográficos
Autores principales: Corwin, David, Holdsworth, Clay, Rockne, Russell C., Trister, Andrew D., Mrugala, Maciej M., Rockhill, Jason K., Stewart, Robert D., Phillips, Mark, Swanson, Kristin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827144/
https://www.ncbi.nlm.nih.gov/pubmed/24265748
http://dx.doi.org/10.1371/journal.pone.0079115