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Avian Influenza Virus H3 Hemagglutinin May Enable High Fitness of Novel Human Virus Reassortants

Reassortment of influenza A virus genes enables antigenic shift resulting in the emergence of pandemic viruses with novel hemagglutinins (HA) acquired from avian strains. Here, we investigated whether historic and contemporary avian strains with different replication capacity in human cells can dona...

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Detalles Bibliográficos
Autores principales: Kreibich, Anne, Stech, Olga, Hundt, Jana, Ziller, Mario, Mettenleiter, Thomas C., Stech, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827155/
https://www.ncbi.nlm.nih.gov/pubmed/24265752
http://dx.doi.org/10.1371/journal.pone.0079165