A New Mutation of the Atoh1 Gene in Mice with Normal Life Span Allows Analysis of Inner Ear and Cerebellar Phenotype in Aging

Atoh1 is a transcription factor that regulates neural development in multiple tissues and is conserved among species. Prior mouse models of Atoh1, though effective and important in the evolution of our understanding of the gene, have been limited by perinatal lethality. Here we describe a novel poin...

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Detalles Bibliográficos
Autores principales: Sheykholeslami, Kianoush, Thimmappa, Vikrum, Nava, Casey, Bai, Xiaohui, Yu, Heping, Zheng, Tihua, Zhang, Zhaoqiang, Li, Sheng Li, Liu, Shuqing, Zheng, Qing Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827170/
https://www.ncbi.nlm.nih.gov/pubmed/24265785
http://dx.doi.org/10.1371/journal.pone.0079791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827170/
https://www.ncbi.nlm.nih.gov/pubmed/24265785
http://dx.doi.org/10.1371/journal.pone.0079791

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