Effect of Oxygen on Cardiac Differentiation in Mouse iPS Cells: Role of Hypoxia Inducible Factor-1 and Wnt/Beta-Catenin Signaling

BACKGROUND: Disturbances in oxygen levels have been found to impair cardiac organogenesis. It is known that stem cells and differentiating cells may respond variably to hypoxic conditions, whereby hypoxia may enhance stem cell pluripotency, while differentiation of multiple cell types can be restric...

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Detalles Bibliográficos
Autores principales: Medley, Tanya L., Furtado, Milena, Lam, Nicholas T., Idrizi, Rejhan, Williams, David, Verma, Paul J., Costa, Mauro, Kaye, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827186/
https://www.ncbi.nlm.nih.gov/pubmed/24265804
http://dx.doi.org/10.1371/journal.pone.0080280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827186/
https://www.ncbi.nlm.nih.gov/pubmed/24265804
http://dx.doi.org/10.1371/journal.pone.0080280

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