Leukocytosis and Enhanced Susceptibility to Endotoxemia but Not Atherosclerosis in Adrenalectomized APOE Knockout Mice

Hyperlipidemic apolipoprotein E (APOE) knockout mice show an enhanced level of adrenal-derived anti-inflammatory glucocorticoids. Here we determined in APOE knockout mice the impact of total removal of adrenal function through adrenalectomy (ADX) on two inflammation-associated pathologies, endotoxem...

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Detalles Bibliográficos
Autores principales: Hoekstra, Menno, Frodermann, Vanessa, van den Aardweg, Tim, van der Sluis, Ronald J., Kuiper, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827228/
https://www.ncbi.nlm.nih.gov/pubmed/24265824
http://dx.doi.org/10.1371/journal.pone.0080441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827228/
https://www.ncbi.nlm.nih.gov/pubmed/24265824
http://dx.doi.org/10.1371/journal.pone.0080441

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