L-Plastin Nanobodies Perturb Matrix Degradation, Podosome Formation, Stability and Lifetime in THP-1 Macrophages

Podosomes are cellular structures acting as degradation ‘hot-spots’ in monocytic cells. They appear as dot-like structures at the ventral cell surface, enriched in F-actin and actin regulators, including gelsolin and L-plastin. Gelsolin is an ubiquitous severing and capping protein, whereas L-plasti...

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Detalles Bibliográficos
Autores principales: De Clercq, Sarah, Boucherie, Ciska, Vandekerckhove, Joël, Gettemans, Jan, Guillabert, Aude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827245/
https://www.ncbi.nlm.nih.gov/pubmed/24236012
http://dx.doi.org/10.1371/journal.pone.0078108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827245/
https://www.ncbi.nlm.nih.gov/pubmed/24236012
http://dx.doi.org/10.1371/journal.pone.0078108

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