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MDM2 Promotes Invasion and Metastasis in Invasive Ductal Breast Carcinoma by Inducing Matrix Metalloproteinase-9

The molecular mechanisms that underpin invasive ductal breast cancer (IDC) invasion and metastasis are incompletely understood. The oncogene, mouse double minute 2 (MDM2), has been implicated in the pathogenesis of numerous cancers, where it stimulates the expression of matrix metalloproteinase 9 (M...

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Detalles Bibliográficos
Autores principales: Chen, Xiaofeng, Qiu, Jinrong, Yang, Dapeng, Lu, Jianlei, Yan, Caiyun, Zha, Xiaoming, Yin, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827260/
https://www.ncbi.nlm.nih.gov/pubmed/24236052
http://dx.doi.org/10.1371/journal.pone.0078794