The Effect of Factor VIII Deficiencies and Replacement and Bypass Therapies on Thrombus Formation under Venous Flow Conditions in Microfluidic and Computational Models

Clinical evidence suggests that individuals with factor VIII (FVIII) deficiency (hemophilia A) are protected against venous thrombosis, but treatment with recombinant proteins can increase their risk for thrombosis. In this study we examined the dynamics of thrombus formation in individuals with hem...

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Detalles Bibliográficos
Autores principales: Onasoga-Jarvis, Abimbola A., Leiderman, Karin, Fogelson, Aaron L., Wang, Michael, Manco-Johnson, Marilyn J., Di Paola, Jorge A., Neeves, Keith B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827262/
https://www.ncbi.nlm.nih.gov/pubmed/24236042
http://dx.doi.org/10.1371/journal.pone.0078732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827262/
https://www.ncbi.nlm.nih.gov/pubmed/24236042
http://dx.doi.org/10.1371/journal.pone.0078732

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