Arx Polyalanine Expansion in Mice Leads to Reduced Pancreatic α-Cell Specification and Increased α-Cell Death

ARX/Arx is a homeodomain-containing transcription factor necessary for the specification and early maintenance of pancreatic endocrine α-cells. Many transcription factors important to pancreas development, including ARX/Arx, are also crucial for proper brain development. Although null mutations of A...

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Detalles Bibliográficos
Autores principales: Wilcox, Crystal L., Terry, Natalie A., May, Catherine Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827280/
https://www.ncbi.nlm.nih.gov/pubmed/24236044
http://dx.doi.org/10.1371/journal.pone.0078741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827280/
https://www.ncbi.nlm.nih.gov/pubmed/24236044
http://dx.doi.org/10.1371/journal.pone.0078741

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