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Overexpressing STAMP2 Improves Insulin Resistance in Diabetic ApoE(−/−)/LDLR(−/−) Mice via Macrophage Polarization Shift in Adipose Tissues

STAMP2 is a counterregulator of inflammation and insulin resistance. The aim of this study is to investigate whether activation of STAMP2 improves insulin resistance by regulating macrophage polarization in adipose tissues. The diabetic ApoE(−/−)/LDLR(−/−) mouse model was induced by high-fat diet an...

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Detalles Bibliográficos
Autores principales: Han, Lu, Tang, Meng-Xiong, Ti, Yun, Wang, Zhi-Hao, Wang, Jia, Ding, Wen-Yuan, Wang, Hua, Zhang, Yun, Zhang, Wei, Zhong, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827284/
https://www.ncbi.nlm.nih.gov/pubmed/24236066
http://dx.doi.org/10.1371/journal.pone.0078903