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Role of Tumor Necrosis Factor-α in the Human Systemic Endotoxin-Induced Transcriptome

TNFα has been implicated in the pathogenesis of various inflammatory diseases. Different strategies to inhibit TNFα in patients with sepsis and chronic inflammatory conditions have shown contrasting outcomes. Although TNFα inhibitors are widely used in clinical practice, the impact of TNFα antagonis...

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Detalles Bibliográficos
Autores principales: Scicluna, Brendon P., van 't Veer, Cornelis, Nieuwdorp, Max, Felsmann, Karen, Wlotzka, Britta, Stroes, Erik S. G., van der Poll, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827317/
https://www.ncbi.nlm.nih.gov/pubmed/24236088
http://dx.doi.org/10.1371/journal.pone.0079051