Cargando…

KCTD20, a relative of BTBD10, is a positive regulator of Akt

BACKGROUND: BTBD10 binds to Akt and protein phosphatase 2A (PP2A) and inhibits the PP2A-mediated dephosphorylation of Akt, thereby keeping Akt activated. Previous studies have suggested that BTBD10 plays an important role in preventing motor neuronal death and accelerating the growth of pancreatic b...

Descripción completa

Detalles Bibliográficos
Autores principales: Nawa, Mikiro, Matsuoka, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827329/
https://www.ncbi.nlm.nih.gov/pubmed/24156551
http://dx.doi.org/10.1186/1471-2091-14-27