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KCTD20, a relative of BTBD10, is a positive regulator of Akt
BACKGROUND: BTBD10 binds to Akt and protein phosphatase 2A (PP2A) and inhibits the PP2A-mediated dephosphorylation of Akt, thereby keeping Akt activated. Previous studies have suggested that BTBD10 plays an important role in preventing motor neuronal death and accelerating the growth of pancreatic b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827329/ https://www.ncbi.nlm.nih.gov/pubmed/24156551 http://dx.doi.org/10.1186/1471-2091-14-27 |