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Androgen Receptor Activity Is Affected by Both Nuclear Matrix Localization and the Phosphorylation Status of the Heterogeneous Nuclear Ribonucleoprotein K in Anti-Androgen-Treated LNCaP Cells

The androgen receptor (AR) plays a central role in the development and progression of prostate cancer (PCa) and anti-androgen therapy is a standard treatment. Unfortunately, after a few years, the majority of patients progress, developing androgen-independent PCa. AR-driven gene transcription recrui...

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Detalles Bibliográficos
Autores principales: Barboro, Paola, Borzì, Luana, Repaci, Erica, Ferrari, Nicoletta, Balbi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827347/
https://www.ncbi.nlm.nih.gov/pubmed/24236111
http://dx.doi.org/10.1371/journal.pone.0079212