MDR-ER: Balancing Functions for Adjusting the Ratio in Risk Classes and Classification Errors for Imbalanced Cases and Controls Using Multifactor-Dimensionality Reduction

BACKGROUND: Determining the complex relationship between diseases, polymorphisms in human genes and environmental factors is challenging. Multifactor dimensionality reduction (MDR) has proven capable of effectively detecting statistical patterns of epistasis. However, MDR has its weakness in accurat...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Cheng-Hong, Lin, Yu-Da, Chuang, Li-Yeh, Chen, Jin-Bor, Chang, Hsueh-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827354/
https://www.ncbi.nlm.nih.gov/pubmed/24236125
http://dx.doi.org/10.1371/journal.pone.0079387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827354/
https://www.ncbi.nlm.nih.gov/pubmed/24236125
http://dx.doi.org/10.1371/journal.pone.0079387

Ejemplares similares