Transforming Growth Factor β Inhibits Platelet Derived Growth Factor-Induced Vascular Smooth Muscle Cell Proliferation via Akt-Independent, Smad-Mediated Cyclin D1 Downregulation

In adult tissue, vascular smooth muscle cells (VSMCs) exist in a differentiated phenotype, which is defined by the expression of contractile proteins and lack of proliferation. After vascular injury, VSMC adopt a synthetic phenotype associated with proliferation, migration and matrix secretion. The...

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Detalles Bibliográficos
Autores principales: Martin-Garrido, Abel, Williams, Holly C., Lee, Minyoung, Seidel-Rogol, Bonnie, Ci, Xinpei, Dong, Jin-Tang, Lassègue, Bernard, Martín, Alejandra San, Griendling, Kathy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827379/
https://www.ncbi.nlm.nih.gov/pubmed/24236150
http://dx.doi.org/10.1371/journal.pone.0079657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827379/
https://www.ncbi.nlm.nih.gov/pubmed/24236150
http://dx.doi.org/10.1371/journal.pone.0079657

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