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Runx3-mediated Transcriptional Program in Cytotoxic Lymphocytes

The transcription factor Runx3 is highly expressed in CD8(+) T and NK cytotoxic lymphocytes and is required for their effective activation and proliferation but molecular insights into the transcription program regulated by Runx3 in these cells are still missing. Using Runx3-ChIP-seq and transcripto...

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Detalles Bibliográficos
Autores principales: Lotem, Joseph, Levanon, Ditsa, Negreanu, Varda, Leshkowitz, Dena, Friedlander, Gilgi, Groner, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827420/
https://www.ncbi.nlm.nih.gov/pubmed/24236182
http://dx.doi.org/10.1371/journal.pone.0080467