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Magnesium Sulfate Protects Against the Bioenergetic Consequences of Chronic Glutamate Receptor Stimulation

Extracellular glutamate is elevated following brain ischemia or trauma and contributes to neuronal injury. We tested the hypothesis that magnesium sulfate (MgSO(4), 3 mM) protects against metabolic failure caused by excitotoxic glutamate exposure. Rat cortical neuron preparations treated in medium a...

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Detalles Bibliográficos
Autores principales: Clerc, Pascaline, Young, Christina A., Bordt, Evan A., Grigore, Alina M., Fiskum, Gary, Polster, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827425/
https://www.ncbi.nlm.nih.gov/pubmed/24236167
http://dx.doi.org/10.1371/journal.pone.0079982