Genetic Deletion of Afadin Causes Hydrocephalus by Destruction of Adherens Junctions in Radial Glial and Ependymal Cells in the Midbrain

Adherens junctions (AJs) play a role in mechanically connecting adjacent cells to maintain tissue structure, particularly in epithelial cells. The major cell–cell adhesion molecules at AJs are cadherins and nectins. Afadin binds to both nectins and α-catenin and recruits the cadherin-β-catenin compl...

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Detalles Bibliográficos
Autores principales: Yamamoto, Hideaki, Maruo, Tomohiko, Majima, Takashi, Ishizaki, Hiroyoshi, Tanaka-Okamoto, Miki, Miyoshi, Jun, Mandai, Kenji, Takai, Yoshimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827428/
https://www.ncbi.nlm.nih.gov/pubmed/24236178
http://dx.doi.org/10.1371/journal.pone.0080356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827428/
https://www.ncbi.nlm.nih.gov/pubmed/24236178
http://dx.doi.org/10.1371/journal.pone.0080356

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