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The Anti-Tumor Effects and Molecular Mechanisms of Suberoylanilide Hydroxamic Acid (SAHA) on the Aggressive Phenotypes of Ovarian Carcinoma Cells

Histone deacetylase inhibitors (HDACi), such as suberoylanilide hydroxamic acid (SAHA), have been shown to act selectively on gene expression, and are potent inducers of growth arrest, differentiation and apoptosis in various types of cancers in vitro and in vivo. This study aimed to elucidate the a...

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Detalles Bibliográficos
Autores principales: Chen, Shuo, Zhao, Yang, Gou, Wen-feng, Zhao, Shuang, Takano, Yasuo, Zheng, Hua-chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827455/
https://www.ncbi.nlm.nih.gov/pubmed/24236158
http://dx.doi.org/10.1371/journal.pone.0079781