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Dopamine and Pain Sensitivity: Neither Sulpiride nor Acute Phenylalanine and Tyrosine Depletion Have Effects on Thermal Pain Sensations in Healthy Volunteers

Based on animal studies and some indirect clinical evidence, dopamine has been suggested to have anti-nociceptive effects. Here, we investigated directly the effects of increased and decreased availability of extracellular dopamine on pain perception in healthy volunteers. In Study 1, participants i...

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Detalles Bibliográficos
Autores principales: Becker, Susanne, Ceko, Marta, Louis-Foster, Mytsumi, Elfassy, Nathaniel M., Leyton, Marco, Shir, Yoram, Schweinhardt, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827462/
https://www.ncbi.nlm.nih.gov/pubmed/24236199
http://dx.doi.org/10.1371/journal.pone.0080766