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The Role of Metabotropic Glutamate Receptor 5 on the Stromal Cell-Derived Factor-1/CXCR4 System in Oral Cancer

We have demonstrated that blocking CXCR4 may be a potent anti-metastatic therapy for CXCR4-related oral cancer. However, as CXCR4 antagonists are currently in clinical use to induce the mobilization of hematopoietic stem cells, continuous administration as an inhibitor for the metastasis may lead to...

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Detalles Bibliográficos
Autores principales: Kuribayashi, Nobuyuki, Uchida, Daisuke, Kinouchi, Makoto, Takamaru, Natsumi, Tamatani, Tetsuya, Nagai, Hirokazu, Miyamoto, Youji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827474/
https://www.ncbi.nlm.nih.gov/pubmed/24236200
http://dx.doi.org/10.1371/journal.pone.0080773