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The Antiepileptic Drug Levetiracetam Suppresses Non-Convulsive Seizure Activity and Reduces Ischemic Brain Damage in Rats Subjected to Permanent Middle Cerebral Artery Occlusion

The antiepileptic drug Levetiracetam (Lev) has neuroprotective properties in experimental stroke, cerebral hemorrhage and neurotrauma. In these conditions, non-convulsive seizures (NCSs) propagate from the core of the focal lesion into perilesional tissue, enlarging the damaged area and promoting ep...

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Detalles Bibliográficos
Autores principales: Cuomo, Ornella, Rispoli, Vincenzo, Leo, Antonio, Politi, Giovanni Bosco, Vinciguerra, Antonio, di Renzo, Gianfranco, Cataldi, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827478/
https://www.ncbi.nlm.nih.gov/pubmed/24236205
http://dx.doi.org/10.1371/journal.pone.0080852