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The Antiepileptic Drug Levetiracetam Suppresses Non-Convulsive Seizure Activity and Reduces Ischemic Brain Damage in Rats Subjected to Permanent Middle Cerebral Artery Occlusion
The antiepileptic drug Levetiracetam (Lev) has neuroprotective properties in experimental stroke, cerebral hemorrhage and neurotrauma. In these conditions, non-convulsive seizures (NCSs) propagate from the core of the focal lesion into perilesional tissue, enlarging the damaged area and promoting ep...
Autores principales: | Cuomo, Ornella, Rispoli, Vincenzo, Leo, Antonio, Politi, Giovanni Bosco, Vinciguerra, Antonio, di Renzo, Gianfranco, Cataldi, Mauro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827478/ https://www.ncbi.nlm.nih.gov/pubmed/24236205 http://dx.doi.org/10.1371/journal.pone.0080852 |
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