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Increased Cell Surface Free Thiols Identify Effector CD8(+) T Cells Undergoing T Cell Receptor Stimulation
Recognition of peptide Major Histocompatibility Complexes (MHC) by the T cell receptor causes rapid production of reactive oxygen intermediates (ROI) in naïve CD8(+) T cells. Because ROI such as H(2)O(2) are membrane permeable, mechanisms must exist to prevent overoxidation of surface proteins. In t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827480/ https://www.ncbi.nlm.nih.gov/pubmed/24236211 http://dx.doi.org/10.1371/journal.pone.0081134 |