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Increased Cell Surface Free Thiols Identify Effector CD8(+) T Cells Undergoing T Cell Receptor Stimulation

Recognition of peptide Major Histocompatibility Complexes (MHC) by the T cell receptor causes rapid production of reactive oxygen intermediates (ROI) in naïve CD8(+) T cells. Because ROI such as H(2)O(2) are membrane permeable, mechanisms must exist to prevent overoxidation of surface proteins. In t...

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Detalles Bibliográficos
Autores principales:	Pellom, Samuel Troy, Michalek, Ryan D., Crump, Katie E., Langston, P. Kent, Juneau, Daniel G., Grayson, Jason M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827480/ https://www.ncbi.nlm.nih.gov/pubmed/24236211 http://dx.doi.org/10.1371/journal.pone.0081134

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