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Downregulation of the H-2K(d) gene by siRNA affects the cytotoxicity of murine LAK cells
To investigate the effect of the H-2K(d) gene on the lymphocyte membrane, we constructed a small interfering RNA (siRNA) that targets the H-2K(d) gene and compared the cytotoxicity of mouse lymphokine-activated killer (LAK) cells with different H-2K(d) expression states. H-2K(d)-targeting siRNA was...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827616/ https://www.ncbi.nlm.nih.gov/pubmed/24206544 http://dx.doi.org/10.1186/1475-2867-13-112 |