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Molecular Network Analysis of T-Cell Transcriptome Suggests Aberrant Regulation of Gene Expression by NF-κB As a Biomarker for Relapse of Multiple Sclerosis

Molecular mechanisms responsible for acute relapse of multiple sclerosis (MS) remain currently unknown. The aim of this study is to identify the relapse-specific biomarker genes in T lymphocytes of relapsing-remitting MS (RRMS). Total RNA of CD3(+) T cells isolated from six RRMS patients taken at th...

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Detalles Bibliográficos
Autores principales: Satoh, Jun-ichi, Misawa, Tamako, Tabunoki, Hiroko, Yamamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827813/
https://www.ncbi.nlm.nih.gov/pubmed/18776589
http://dx.doi.org/10.1155/2008/824640