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Complementarity of Binding Motifs is a General Property of HLA-A and HLA-B Molecules and Does Not Seem to Effect HLA Haplotype Composition

Different human leukocyte antigen (HLA) haplotypes (i.e., the specific combinations of HLA-A, -B, -DR alleles inherited together from one parent) are observed in different frequencies in human populations. Some haplotypes, like HLA-A1-B8, are very frequent, reaching up to 10% in the Caucasian popula...

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Detalles Bibliográficos
Autores principales: Rao, Xiangyu, De Boer, Rob J., van Baarle, Debbie, Maiers, Martin, Kesmir, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827838/
https://www.ncbi.nlm.nih.gov/pubmed/24294213
http://dx.doi.org/10.3389/fimmu.2013.00374