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Knowledge-based compact disease models identify new molecular players contributing to early-stage Alzheimer’s disease

BACKGROUND: High-throughput profiling of human tissues typically yield as results the gene lists comprised of a mix of relevant molecular entities with multiple false positives that obstruct the translation of such results into mechanistic hypotheses. From general probabilistic considerations, gene...

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Detalles Bibliográficos
Autores principales: Mayburd, Anatoly, Baranova, Ancha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827844/
https://www.ncbi.nlm.nih.gov/pubmed/24196233
http://dx.doi.org/10.1186/1752-0509-7-121