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Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay

BACKGROUND: The combination of time-lapse imaging of live cells with high-throughput perturbation assays is a powerful tool for genetics and cell biology. The Mitocheck project employed this technique to associate thousands of genes with transient biological phenotypes in cell division, cell death a...

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Detalles Bibliográficos
Autores principales: Pau, Gregoire, Walter, Thomas, Neumann, Beate, Hériché, Jean-Karim, Ellenberg, Jan, Huber, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827932/
https://www.ncbi.nlm.nih.gov/pubmed/24131777
http://dx.doi.org/10.1186/1471-2105-14-308