Cargando…

Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay

BACKGROUND: The combination of time-lapse imaging of live cells with high-throughput perturbation assays is a powerful tool for genetics and cell biology. The Mitocheck project employed this technique to associate thousands of genes with transient biological phenotypes in cell division, cell death a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pau, Gregoire, Walter, Thomas, Neumann, Beate, Hériché, Jean-Karim, Ellenberg, Jan, Huber, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827932/ https://www.ncbi.nlm.nih.gov/pubmed/24131777 http://dx.doi.org/10.1186/1471-2105-14-308

Ejemplares similares

Clustering phenotype populations by genome-wide RNAi and multiparametric imaging
por: Fuchs, Florian, et al.
Publicado: (2010)

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains
por: Xiang, Wanqing, et al.
Publicado: (2018)

Correction: Correlative live and super-resolution imaging reveals the dynamic structure of replication domains
por: Xiang, Wanqing, et al.
Publicado: (2018)

The cellular microscopy phenotype ontology
por: Jupp, Simon, et al.
Publicado: (2016)

Profiling DNA damage response following mitotic perturbations
por: S. Pedersen, Ronni, et al.
Publicado: (2016)

EBImage—an R package for image processing with applications to cellular phenotypes
por: Pau, Grégoire, et al.
Publicado: (2010)

Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi
por: Axelsson, Elin, et al.
Publicado: (2011)

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes
por: López-Varea, Ana, et al.
Publicado: (2021)

Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters
por: López-Varea, Ana, et al.
Publicado: (2021)

Simulating structurally variable nuclear pore complexes for microscopy
por: Theiss, Maria, et al.
Publicado: (2023)

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores
por: Isokane, Mayumi, et al.
Publicado: (2016)

GenomeRNAi: a database for cell-based RNAi phenotypes
por: Horn, Thomas, et al.
Publicado: (2007)

Analysis of cell-based RNAi screens
por: Boutros, Michael, et al.
Publicado: (2006)

How can functional annotations be derived from profiles of phenotypic annotations?
por: Serrano-Solano, Beatriz, et al.
Publicado: (2017)

Erratum to: How can functional annotations be derived from profiles of phenotypic annotations?
por: Serrano-Solano, Beatriz, et al.
Publicado: (2017)

GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update
por: Gilsdorf, Moritz, et al.
Publicado: (2010)

Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene
por: Jonchere, Vincent, et al.
Publicado: (2013)

GenomeRNAi: a database for cell-based and in vivo RNAi phenotypes, 2013 update
por: Schmidt, Esther E., et al.
Publicado: (2013)

Live imaging of single nuclear pores reveals unique assembly kinetics and mechanism in interphase
por: Dultz, Elisa, et al.
Publicado: (2010)

Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans
por: Yanos, Melana E, et al.
Publicado: (2012)

Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex
por: Sabinina, Vilma Jimenez, et al.
Publicado: (2021)

The Image Data Explorer: Interactive exploration of image-derived data
por: Muller, Coralie, et al.
Publicado: (2022)

Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation
por: Lehmann, Susann, et al.
Publicado: (2012)

RNAi phenotypes are influenced by the genetic background of the injected strain
por: Kitzmann, Peter, et al.
Publicado: (2013)

RNAi2013: RNAi at Oxford
por: Mulcahy, Laura A, et al.
Publicado: (2013)

Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes
por: Pfender, Sybille, et al.
Publicado: (2015)

A fitness assay for comparing RNAi effects across multiple C. elegans genotypes
por: Elvin, Mark, et al.
Publicado: (2011)

Identification of Neural Outgrowth Genes using Genome-Wide RNAi
por: Sepp, Katharine J., et al.
Publicado: (2008)

Modifiers of notch transcriptional activity identified by genome-wide RNAi
por: Mourikis, Philippos, et al.
Publicado: (2010)

A genome-wide screening for RNAi pathway proteins in Acari
por: Nganso, Beatrice T., et al.
Publicado: (2020)

High throughput RNAi assay optimization using adherent cell cytometry
por: Nabzdyk, Christoph S, et al.
Publicado: (2011)

Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase
por: Moses, Alan M, et al.
Publicado: (2007)

Variations in genome-wide RNAi screens: lessons from influenza research
por: Chou, Yu-Chi, et al.
Publicado: (2015)

A Novel Multiplex Cell Viability Assay for High-Throughput RNAi Screening
por: Gilbert, Daniel F., et al.
Publicado: (2011)

Bacterial Delivery of RNAi Effectors: Transkingdom RNAi
por: Lage, Hermann, et al.
Publicado: (2010)

RNAi2015 – Ten years of RNAi Oxford
por: Bewicke-Copley, Findlay, et al.
Publicado: (2015)

Unsupervised automated high throughput phenotyping of RNAi time-lapse movies
por: Failmezger, Henrik, et al.
Publicado: (2013)

RNAi prevents and reverses phenotypes induced by mutant human ataxin‐1
por: Keiser, Megan S., et al.
Publicado: (2016)

FlyRNAi: the Drosophila RNAi screening center database
por: Flockhart, Ian, et al.
Publicado: (2006)

Asian Citrus Psyllid RNAi Pathway – RNAi evidence
por: Taning, Clauvis N. T., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_i5rt95oclfd4has93788a34ktd