Cargando…

Killer Immunoglobulin-like Receptors (KIR) haplogroups A and B track with Natural Killer Cells and Cytokine Profile in Aged Subjects: Observations from Octo/Nonagenarians in the Belfast Elderly Longitudinal Free-living Aging STudy (BELFAST)

BACKGROUND: Natural Killer Cells (NK) play an important role in detection and elimination of virus-infected, damaged or cancer cells. NK cell function is guided by expression of Killer Immunoglobulin-like Receptors (KIRs) and contributed to by the cytokine milieu. KIR molecules are grouped on NK cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Rea, Irene Maeve, Maxwell, Lynn D, McNerlan, Susan E, Alexander, H Denis, Curran, Martin D, Middleton, Derek, Ross, Owen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827941/
https://www.ncbi.nlm.nih.gov/pubmed/23957956
http://dx.doi.org/10.1186/1742-4933-10-35