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Renewable, recombinant antibodies to histone post-translational modifications

Variability in the quality of antibodies to histone post-translational modifications (PTMs) presents widely recognized hindrance in epigenetics research. Here, by using antibody engineering technologies we produced recombinant antibodies directed to the trimethylated lysine residues of histone H3 wi...

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Detalles Bibliográficos
Autores principales: Hattori, Takamitsu, Taft, Joseph M., Swist, Kalina M., Luo, Hao, Witt, Heather, Slattery, Matthew, Koide, Akiko, Ruthenburg, Alexander J., Krajewski, Krzysztof, Strahl, Brian D., White, Kevin P., Farnham, Peggy J., Zhao, Yingming, Koide, Shohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828030/
https://www.ncbi.nlm.nih.gov/pubmed/23955773
http://dx.doi.org/10.1038/nmeth.2605