Cargando…

T Cell Activation is Determined by the Number of Presented Antigens

[Image: see text] Antigen recognition is a key event during T cell activation. Here, we introduce nanopatterned antigen arrays that mimic the antigen presenting cell surface during T cell activation. The assessment of activation related events revealed the requirement of a minimal density of 90–140...

Descripción completa

Detalles Bibliográficos
Autores principales: Deeg, Janosch, Axmann, Markus, Matic, Jovana, Liapis, Anastasia, Depoil, David, Afrose, Jehan, Curado, Silvia, Dustin, Michael L., Spatz, Joachim P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828117/
https://www.ncbi.nlm.nih.gov/pubmed/24117051
http://dx.doi.org/10.1021/nl403266t