Computational Protein Design Quantifies Structural Constraints on Amino Acid Covariation

Amino acid covariation, where the identities of amino acids at different sequence positions are correlated, is a hallmark of naturally occurring proteins. This covariation can arise from multiple factors, including selective pressures for maintaining protein structure, requirements imposed by a spec...

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Detalles Bibliográficos
Autores principales: Ollikainen, Noah, Kortemme, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828131/
https://www.ncbi.nlm.nih.gov/pubmed/24244128
http://dx.doi.org/10.1371/journal.pcbi.1003313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828131/
https://www.ncbi.nlm.nih.gov/pubmed/24244128
http://dx.doi.org/10.1371/journal.pcbi.1003313

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