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Structure-Based Function Prediction of Uncharacterized Protein Using Binding Sites Comparison

A challenge in structural genomics is prediction of the function of uncharacterized proteins. When proteins cannot be related to other proteins of known activity, identification of function based on sequence or structural homology is impossible and in such cases it would be useful to assess structur...

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Detalles Bibliográficos
Autores principales: Konc, Janez, Hodošček, Milan, Ogrizek, Mitja, Trykowska Konc, Joanna, Janežič, Dušanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828134/
https://www.ncbi.nlm.nih.gov/pubmed/24244144
http://dx.doi.org/10.1371/journal.pcbi.1003341