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In Silico Analysis of Cell Cycle Synchronisation Effects in Radiotherapy of Tumour Spheroids

Tumour cells show a varying susceptibility to radiation damage as a function of the current cell cycle phase. While this sensitivity is averaged out in an unperturbed tumour due to unsynchronised cell cycle progression, external stimuli such as radiation or drug doses can induce a resynchronisation...

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Detalles Bibliográficos
Autores principales: Kempf, Harald, Hatzikirou, Haralampos, Bleicher, Marcus, Meyer-Hermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828142/
https://www.ncbi.nlm.nih.gov/pubmed/24244120
http://dx.doi.org/10.1371/journal.pcbi.1003295