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In Silico Analysis of Cell Cycle Synchronisation Effects in Radiotherapy of Tumour Spheroids
Tumour cells show a varying susceptibility to radiation damage as a function of the current cell cycle phase. While this sensitivity is averaged out in an unperturbed tumour due to unsynchronised cell cycle progression, external stimuli such as radiation or drug doses can induce a resynchronisation...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828142/ https://www.ncbi.nlm.nih.gov/pubmed/24244120 http://dx.doi.org/10.1371/journal.pcbi.1003295 |