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Recruitment of TREX to the Transcription Machinery by Its Direct Binding to the Phospho-CTD of RNA Polymerase II

Messenger RNA (mRNA) synthesis and export are tightly linked, but the molecular mechanisms of this coupling are largely unknown. In Saccharomyces cerevisiae, the conserved TREX complex couples transcription to mRNA export and mediates mRNP formation. Here, we show that TREX is recruited to the trans...

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Detalles Bibliográficos
Autores principales: Meinel, Dominik M., Burkert-Kautzsch, Cornelia, Kieser, Anja, O'Duibhir, Eoghan, Siebert, Matthias, Mayer, Andreas, Cramer, Patrick, Söding, Johannes, Holstege, Frank C. P., Sträßer, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828145/
https://www.ncbi.nlm.nih.gov/pubmed/24244187
http://dx.doi.org/10.1371/journal.pgen.1003914