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Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

Approximately one-third of the world's population suffers from chronic helminth infections with no effective vaccines currently available. Antibodies and alternatively activated macrophages (AAM) form crucial components of protective immunity against challenge infections with intestinal helmint...

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Detalles Bibliográficos
Autores principales: Esser-von Bieren, Julia, Mosconi, Ilaria, Guiet, Romain, Piersgilli, Alessandra, Volpe, Beatrice, Chen, Fei, Gause, William C., Seitz, Arne, Verbeek, J. Sjef, Harris, Nicola L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828184/
https://www.ncbi.nlm.nih.gov/pubmed/24244174
http://dx.doi.org/10.1371/journal.ppat.1003771