Cargando…
Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages
Approximately one-third of the world's population suffers from chronic helminth infections with no effective vaccines currently available. Antibodies and alternatively activated macrophages (AAM) form crucial components of protective immunity against challenge infections with intestinal helmint...
Autores principales: | Esser-von Bieren, Julia, Mosconi, Ilaria, Guiet, Romain, Piersgilli, Alessandra, Volpe, Beatrice, Chen, Fei, Gause, William C., Seitz, Arne, Verbeek, J. Sjef, Harris, Nicola L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828184/ https://www.ncbi.nlm.nih.gov/pubmed/24244174 http://dx.doi.org/10.1371/journal.ppat.1003771 |
Ejemplares similares
-
Immune Antibodies and Helminth Products Drive CXCR2-Dependent Macrophage-Myofibroblast Crosstalk to Promote Intestinal Repair
por: Esser-von Bieren, Julia, et al.
Publicado: (2015) -
β‐Glucan receptors on IL‐4 activated macrophages are required for hookworm larvae recognition and trapping
por: Bouchery, Tiffany, et al.
Publicado: (2022) -
Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection
por: Hewitson, James P., et al.
Publicado: (2015) -
Helminthic dehydrogenase drives PGE(2) and IL‐10 production in monocytes to potentiate Treg induction
por: Prodjinotho, Ulrich Fabien, et al.
Publicado: (2022) -
Protocol for immunofluorescence staining of murine helminth-infected intestinal and lung tissues
por: El-Naccache, Darine W., et al.
Publicado: (2023)