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Inhibition of Rho-Kinase by Fasudil Suppresses Formation and Progression of Experimental Abdominal Aortic Aneurysms

OBJECTIVE: Accumulating evidence suggests that inflammatory cell infiltration is crucial pathogenesis during the initiation and progression of abdominal aortic aneurysm (AAA). Given Rho-kinase (ROCK), an important kinase control the actin cytoskeleton, regulates the inflammatory cell infiltration, t...

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Detalles Bibliográficos
Autores principales: Peng, Chen, Gu, Peng, Zhou, Jing, Huang, Jianhua, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828185/
https://www.ncbi.nlm.nih.gov/pubmed/24244631
http://dx.doi.org/10.1371/journal.pone.0080145