Predictive Markers of Efficacy for an Angiopoietin-2 Targeting Therapeutic in Xenograft Models

The clinical efficacy of anti-angiogenic therapies has been difficult to predict, and biomarkers that can predict responsiveness are sorely needed in this era of personalized medicine. CVX-060 is an angiopoietin-2 (Ang2) targeting therapeutic, consisting of two peptides that bind Ang2 with high affi...

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Detalles Bibliográficos
Autores principales: Triana-Baltzer, Gallen, Pavlicek, Adam, Goulart, Ariadne, Huang, Hanhua, Pirie-Shepherd, Steven, Levin, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828186/
https://www.ncbi.nlm.nih.gov/pubmed/24244628
http://dx.doi.org/10.1371/journal.pone.0080132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828186/
https://www.ncbi.nlm.nih.gov/pubmed/24244628
http://dx.doi.org/10.1371/journal.pone.0080132

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