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Predictive Markers of Efficacy for an Angiopoietin-2 Targeting Therapeutic in Xenograft Models
The clinical efficacy of anti-angiogenic therapies has been difficult to predict, and biomarkers that can predict responsiveness are sorely needed in this era of personalized medicine. CVX-060 is an angiopoietin-2 (Ang2) targeting therapeutic, consisting of two peptides that bind Ang2 with high affi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828186/ https://www.ncbi.nlm.nih.gov/pubmed/24244628 http://dx.doi.org/10.1371/journal.pone.0080132 |