Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes

Bacterial DsbA enzymes catalyze oxidative folding of virulence factors, and have been identified as targets for antivirulence drugs. However, DsbA enzymes characterized to date exhibit a wide spectrum of redox properties and divergent structural features compared to the prototypical DsbA enzyme of E...

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Detalles Bibliográficos
Autores principales: Kurth, Fabian, Rimmer, Kieran, Premkumar, Lakshmanane, Mohanty, Biswaranjan, Duprez, Wilko, Halili, Maria A., Shouldice, Stephen R., Heras, Begoña, Fairlie, David P., Scanlon, Martin J., Martin, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828196/
https://www.ncbi.nlm.nih.gov/pubmed/24244651
http://dx.doi.org/10.1371/journal.pone.0080210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828196/
https://www.ncbi.nlm.nih.gov/pubmed/24244651
http://dx.doi.org/10.1371/journal.pone.0080210

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