Cathepsin B Gene Disruption Induced Leishmania donovani Proteome Remodeling Implies Cathepsin B Role in Secretome Regulation

Leishmania cysteine proteases are potential vaccine candidates and drug targets. To study the role of cathepsin B cysteine protease, we have generated and characterized cathepsin B null mutant L. donovani parasites. L. donovani cathepsin B null mutants grow normally in culture, but they show signifi...

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Detalles Bibliográficos
Autores principales: Gerbaba, Teklu Kuru, Gedamu, Lashitew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828211/
https://www.ncbi.nlm.nih.gov/pubmed/24244582
http://dx.doi.org/10.1371/journal.pone.0079951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828211/
https://www.ncbi.nlm.nih.gov/pubmed/24244582
http://dx.doi.org/10.1371/journal.pone.0079951

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